Midway via his occupation, Cees Dekker reinvented himself. Right after many years of hardcore physics, he shifted his concentration to ‘nanobiology’ with the convert of your millennium. A time period he coined himself, for a make any difference of reality.

Our team scientific studies bacterial mobile division and is aiming to represent a ‘bottom up biology’ in synthetic cells that can autonomously divide. Our most important desire lies in cell division, chromatin framework, and spatial Command.

Being a individual, I provide the biblical assignment to discover and use everything in creation for the advantage of my neighbour. I do not encounter any conflict among faith and science. Quite the opposite, my religion stimulates me to do science, to be open up-minded on the globe.’

Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on single molecules and steel clusters

We produce level-of-care diagnostics exam of neglected tropical conditions in resource-limited configurations, based on Crspr/Cas9 detecting of pathogen’s DNA in system fluids.

Example (3) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is proven in grey, the rim of your pore is highlighted in red, plus a 3D rendering with the motion in the DNA rod is exhibited.

We form germs into forms that deviate from their natural phenotype. Specifically, I'll exhibit our capacity to form live E. coli bacteria into novel styles for instance rectangles, squares, triangles and circles.

Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in the cooperative manner

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‘The fantastically subtle way wherein aspects in character perform never ceases to amaze me. If we solve the puzzle of how everyday living arrived into staying, I hope that my amazement for the complexity of development may have increased and with it my awe with the greatness on the Creator.’

Considering ceesdekker.net the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with study from experiments of DNA loop extrusion and supercoiling to DNA translocation by way of nanopores. Much more lately his investigate has focused on researching chromatin construction and mobile division with germs on chip, though he is additionally seeking to eventually build synthetic cells from The underside up.

Nanoscientist Cees Dekker is really an amiable and flamboyant male who appears A lot younger than the sixty two yrs he in fact is – trendy glasses, psychedelic shirt, partaking smile – but not 1 to squander time. He requires his time, but no more than necessary.

By way of example, we think about the nucleopore complicated, a gateway involving the cell nucleus and also the cytoplasm. This is a really intricate program and thus difficult to review within a cell, so we use biomimetics. We reconstruct holes after which you can insert specific factors of the nucleopore advanced to review transportation by way of it at the single-molecule stage.’

It absolutely was an extremely attention-grabbing time, in the course of which I gained lots of assist from Delft College of Technologies, the place I had been a professor at the time, and I started out various collaborations with molecular biologists. That served me discover a good deal.’